Multivoxel 1H-mr spectroscopy as a potential diagnostic tool in the complex diagnosis of multiple sclerosis type conversion: a case report

The onset of progressive deficit in multiple sclerosis (MS) was often determined retrospectively with difficulties diagnostic. This is a case report subtle MS progression. Clinical and structural MRI anamnesis complemented multivoxel 1HMRS examination. patient complained the walking distance reducing, gradually increasing spasticity distal parts lower extremities, unsteadiness when walking, clumsy movements. Choline myoinositol levels were predominantly increased area cingulate gyrus versus other gray matter regions same picture observed adjacent white matter. Multivoxel 1H-MRS represents diagnostic tool that can be very useful complex Measuring chemical-pathological changes diffusely brain tissues may detect distinctive for progression metabolic patterns.